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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a63f70ee31b54dd0f06894664500773d06c2e035f1e483c367a8493386a3d99' 
  AND token = 'xi8LPvN0azMZus6icgJIaN7xEClTUSKEpQfjt1lGyZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}