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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a442c83c293bb2b8f269aacbf342ea5a254117ae09e00f4806263f0dec2a1367' 
  AND token = 'AI0aEeOr/kmSuOHJkbijQzOAraz5fo9CL/55bjJoeEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}