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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a1262d5b011ef92bf3f501b986c01901fb707984389e97d72007cc15c597378' 
  AND token = 'Ko400rm4u7XFl4FrQd0O1GCz2TJljfoe0mkdavzb80o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}