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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfcc9e0a11d8a34ee2c3d7c05e1ca68910d3f5175717f3d27e171bddc6594670' 
  AND token = 'QoGfhroSRWl36YPMBOkAeBaGmRlPSA5kvHdEwEJJjVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}