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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8188e2d05d8d96cc3ecd468c8ea676be7efdcb97a59b3890d220307dcd8ac43f' 
  AND token = '8ONPCvupJdiJZNIjzCSjsLY1wH8UMingeUpzQsqtJzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}