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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e5ea27a09ac655a9d23f78a717f99b00fcc348bd1ed1cf03a75bd282fc7e177' 
  AND token = '1+e3V1V8HhRxEK4+NuGn7cvXDG8GaU63y0C3GYDXPhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}