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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0da18a0c3cd7d1ce0157288daf4fb2c1caf178c45847e9920b4e0d1ae006ee0' 
  AND token = 'O3ShAPUXQxQpHKw9Sua1rHg8uGxqxrMG26eGz8CYlmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}