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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0fef7bcffab613786b18b2ca9b95a1c8a1f742a9428d4702a0779f891cd86c4' 
  AND token = 'Y+IHMWaC4Yi0pp0xnQ8+pPHWsgllx+tOewdGN8e94Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}