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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6b5a8400fae4c5df628cd875c8198af960b3f4e65ef87cefbdad307d632b30' 
  AND token = '/rErx5nW7mzLc4e+NkPFkLLgppyjgIoSs9fXHfjbXBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}