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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33a89b786d5d8287c257f3683b95f621b28c0fccfd3928e310d6f626fd94333a' 
  AND token = 'Z75+jPbJXCvQ5ILCJ92mqWklDonp26J+5raZ/AXpphc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}