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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec1a7db68ac56710ed9668ceb0e39320646ef4f872496dbe03d1a2011a8e664e' 
  AND token = 'nNR6VG+sCe0YRjRp4kAF8jF+GEFvgIdtBHuW8cKGG4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}