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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf9bbeef57ba857e84216ed870374f331a46c2f68d43a012381e197d025f3a5' 
  AND token = 'wiijRWtQ/IjkEj6P2WZVOnEIdwyXroJwDaZVX1uKLWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}