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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1a273a40130bd1367eaffc5e637224abf25a9661e169185c47b949c713f59c8' 
  AND token = 'nEspfIOPay+xGTw1PuA4Hh+IdZ+ZDm8ehTpmvHc61ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}