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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00b74712045722a38bd945abb2d047b8eea7945bb11844b94a9b89eb916778bc' 
  AND token = 'RXGSqPBkc7SDMSBpQz1BGRksZPxwfwX5L1dnj+md0mk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}