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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a852f233b146a18945e0a34b2a8f37c44704c9f5e78023e52dd42a4f9508a54' 
  AND token = '2ZwpXIjFjj78T96piUUHSBWZIdjJQ2Xqc9kUe0k2UCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}