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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59abf73376d6d9abbd1f6cf2716720528595ca6b054f2b1c4e7c5661e4d137a7' 
  AND token = 'ts6bP6OeAk1B1nYTw8eYfxoABlkLLcT1OoNEE0/348k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}