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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78a1f1bca02dffe7aba7b9f7dad455c6ec1f2c2b2e4d3c87b318c25056b51a2d' 
  AND token = '+oLZu+lEHGhc7+r+Q+qMyyrEZKCM7iFt/pc6h/8kPr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}