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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07ef9ef12c96eba31e2293b7d1c9e3cc4d01621639491fb4792e170ca0d53bc7' 
  AND token = '1/lHOA1N2EO6nI3XwBrO10r3CIcVwfxVXn1PIR61k8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}