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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54de220bb38592f865b08be926d93ef35b92c73d7506b3319db440dc45c955eb' 
  AND token = '2wxPOFoXqkI9siF5xxQk2KnDGgRqXSil2tQikgTIsU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}