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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd18685d5b304cbd0833d1c22d3d518cb654403bf954459328ba47c6edda3c3c' 
  AND token = 'SJ3K7fKLdYeilXC4s/FLqU3rW9gog176NVJURQDC8sQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}