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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a598797b676a51e99d246b87a6eca8516a7ecf8cdea83f2626ebfbfa2da344a' 
  AND token = 'HBywcJYsC7HLWlxIyYh8nOGEjm9e9K7keIQQNw2x2fQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}