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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1515bda8d86527bd6ceffdae890c34657c8f2f8d26027d68838ca29d60269ee5' 
  AND token = 'hjCQmCd8+QZpIiS6ykb0+pgmXL+IAxTH0s7Ne076Py0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}