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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f90917a2f4324487c0e921d40fdfb505191833d0a876642aafe967038f3b49' 
  AND token = 'm5QgFzWEk8E3rWpgqMRTN9B1yigiK4/uitNz2fhXWcw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}