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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b26bc07298ad824e9ae4fa4f18bdb0278ff854a1abf36145da4549a4bbda90' 
  AND token = 'Q5+I24SV6tI6ta08yHbxra97QXUR8yBNPjdPprH0aZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}