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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf036c3d0c38fe2ebe90d9c4a80266b52d48df19017128234dde180123123312' 
  AND token = 'X9wliHwm6UX/8IK5f9CuTOyrUxvTzNZ0kqPUUjCE65M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}