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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ff3f72862b0b468728d217aceb83265be72b4361536d0a8e8b10debaf173c6b' 
  AND token = 'pyIXbjHrXdVjSvaFBPMofH2VZyx1lHf/33ju+EnSFZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}