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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d26330d37d3110f2875d13939e5c1bd6f31e77afe6038e93bf7a20a1f30acb5' 
  AND token = 'ROWqa3MILP29UdcM1UAgVXYXI0WwUwaZjHYyKM+fZog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}