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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '405e6270d9c359b659de53e374eeb51d34771ddf796ca96dcd57a90ccd5db7b6' 
  AND token = 'TmGpdT5G4Z6C15OaVCgsU5bsRm0JP1tqIBfA6Valb/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}