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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26619f125500fad8e2e3941f7560ea3f3a80b3fa5f5b2dee11b79bf29124722e' 
  AND token = 'PQ5EU0IkiG3II32ctN1OIGs9+9PZMio7ZybUXg41UQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}