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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '507c21670b61b25bea7972b9a6565dfa6e7b45cceee51374da363433a136430c' 
  AND token = '1JCiQWxSNR8eRUvLf/6T3M6481gdHAAVvw/86w7/tsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}