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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb8ed2c4d045f314a04005fd3311a7a72accc972061405f97fdce7697c01f7c7' 
  AND token = 'c2Bv3f6hL5xB9nezg2+d/O0cBT74LX7fpVQ2MZWQMwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}