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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8deaeaecf9605b70bed5371ea78b4deb046b9c8df17d9f6376b92ec9c5a717a8' 
  AND token = 'x2tOK2R9imvEd7GSeozfX0rG+DiiuiXfZ37AAMc1/zA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}