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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '937b3cad57e5d4ff0a4f0f70ba2679d6fa4676d2782ebc3bd99f3f6f33575334' 
  AND token = 'TYDjwd1FdQmXvHjOCI4eAIltQKvLBSIIUT0UTut9GY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}