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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e10b7f6d03a433ef57cc15bf5eef1d98dec0b30b661f235dda389fa56141bd9' 
  AND token = 'IH6ltX/kR6//Tn52NtZ8sJy/OyPcukyuqUcYkV4pLYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}