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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4f1fc0c41599f3f6d6ca93d3ebab59c4af53516375c213d87cf45e74dd36c0' 
  AND token = 'tpbkdlt+GjQcS0AbDzpZ7yIhHH0+8MlZakwrk6tnzdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}