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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20599273e403193db6a99a3c12f16d2411f77c1dba7e58dabd25ac06da055222' 
  AND token = '6pKt4P6GHu2Or8kg1cDvENhZxhuY9pyxH8FwJVt6b2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}