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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a24a635b2ee9af58e59297800b4312c739767657218399790c70e60a9f8d4a79' 
  AND token = 'rEKi3VSv+IaW5Jb9yh9jam0piMM5jBoRz+JrgyTBcSo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}