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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fb3913e12402c707cb35f72f6250071372a2fcd11ca49374ed3082ef59daf1d' 
  AND token = 'aYRH7X6LYcpS/QQrzm0F+UiOEQheT0t89RF21JBgQD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}