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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1685a51903d38e714beb369b0d41b4ea1b074c45dc9a5b13e0a2c27914f1a06' 
  AND token = 'kyu77WWYLQKRUi3qIFzSiKoyDOBeO2ZBDDNH5GXmiCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}