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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5d0742078cc3f0d0dc711b2d6aa3aa5266fed96912192dddddbb88d7c89d254' 
  AND token = '+UkI0cm+LGP5DdMpSj3yo4cz1YDDDFW6I1Dma3X5Ce4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}