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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53398860e9a81680fddfeec87384be07ad783346c4be8aa3864692012dec5629' 
  AND token = '3aatp3CZORET5RgJIqhuhSfp3yt6hszRcmUg95TF6XY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}