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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9430339e5be098e8390d1376c21da776456869eb9b5c353c4cc5b7cbf652cacf' 
  AND token = '78Wo41LPnGHqebdqhG54jK9ATCoJMYf8zVjV3Zl6iHE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}