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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14858a0e02fc082b855297251f1ccbfe999057fe4294c85f8c0ce7f4cd262a31' 
  AND token = 'L7D8q0zKkYnOEDSB0wDDOlRXcFXd5PaSdUdoPLZdnN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}