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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7be4a534217c860447be1303fe5ca8850d01d9459a91c37511e165cf37178f02' 
  AND token = 'Qpjnkarco+ladCp398fhyhNVmNHunAWrqYbNlk0jc6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}