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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efefe0a7ca95160a42be7ed0d5cf8989c70d5777115ff90aac70d3afbb6269d8' 
  AND token = 'po6utkFtVRW8mYK58U72Ua7pd5XlZqCwzcjdMY4mfXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}