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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff724edc602986bf1db60893692bb6f6b1b46be100080f42f0563cda39fb7cf' 
  AND token = 'tt0NLFXoJbCfV/8uG3rc+lpzVZRyE+Bn74SmhkFcFQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}