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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a4c7a67be161b460c47fa8d6b7053a38aaa81e1b2b15c2a179274366829d0bf' 
  AND token = 'gqn99wRPTgBoAfN6Mi2LH7eNvjGrlH5tWiTx6AvZVUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}