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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b0a8f227e6a8315a456e29fb2c2667a86c089eee2a6c25586260c6d63bee4d' 
  AND token = 'kKHFIq0J8n8LPaHEj+L8UMgD7ha6VuIkas/aJk5DfzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}