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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b11160c1258322c39e9ecdfd07a3cdbe2cd33acabc830f882115da01667193a0' 
  AND token = 'dbOp0ry5XDGNQngTaTXTY92p4MvzFXVlAD8UUNHH+X0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}