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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d05780509b01c0568f138d5d21c4934543490a45c3508a1e1329301d763e8b2' 
  AND token = '/il6s6GY/ywNhhjR51KauGEolMrQz7BIxQ9tvLae6RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}